Cyclophosphamide

Abi has started on cyclophosphamide, the second phase of 'conditioning' her marrow before transplant. Hopefully this is the last chemo drug she'll get, as it has been knocking her around a bit unfortunately. Last night was a couple of hours of nausea and vomiting, and a little more again tonight. This has been less than we anticipated given the quick onset yesterday after dosing, however the anti-nausea drugs were better timed today so are hopefully helping. She battles through it all pretty well as we've come to expect, and has even managed to have something to eat this afternoon. Hopefully she continues to eat a little, as this will help her gut recover more quickly (the gut lining is affected by chemo as much as the cancer cells, hence the nausea). Either way she'll get a nasal-gastric tube on Wednesday to help her through things down the track.

So, not a lot else to report, other than her blood continues to be good. The heavy doses of drugs are starting to take effect though, and she is a little flatter throughout the day and is losing her appetite. Two more doses of this drug to go, so fingers crossed the cumulative side effects don't add up too much mid-week before transplant day on Thursday.